Large-scale identification of secondary metabolites, metabolic pathways and their genes in the model tree poplar.

Poplar is an important woody biomass crop and at the same time the model of choice for molecular research in trees. Although there is steady progress in resolving the functions of unknown genes, the identities of most secondary metabolites in poplar remain unknown. The lack of metabolite identities in experimental systems is a true gap in information content, and impedes obtaining deep insight into the complex biology of living systems.

Relevance of lignin research for a more sustainable society

Plants use sunlight and water to capture CO2 from the atmosphere to build their biomass. That biomass can then be converted to products that are nowadays made from fossil resources such as petroleum. Whereas the use of fossil resources leads to a net increase of CO2 into the atmosphere (e.g. when burning it as fuel), this is not the case when using plant biomass. For this reason, plant biomass is considered a renewable, carbon-neutral resource

Translational research in bio-energy crops

A major objective of the group is to demonstrate, in field trials, that the improved biomass processing efficiency of the engineered, greenhouse-grown biomass crops is maintained when plants are grown in the field. This is especially relevant for poplar, as trees are harvested in winter when leaves have been shed and the wood formation program has ended. But also for maize, plants grown in the field are phenotypically very different from those grown in the greenhouse due to the very different environment.

Systematic identification of secondary metabolite structures in Arabidopsis and biomass crops

A main bottleneck in our gene discovery studies is that the identity of most metabolites is unknown. We can only understand the response to pathway perturbations, when we know the identity of the differentially accumulating compounds, e.g. in reverse genetics studies where we aim at identifying the substrate for an enzyme.